Research Peptide
Semax
ACTH(4-10) synthetic analogue · heptapeptide
$52
Includes 5mg vials. Free shipping over $150.
Choose size
Quantity
HPLC ≥ 99%
LC-MS Verified
Sterile Vial
Batch COA
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This product is a research compound and must not be used in humans or animals. Placing an order confirms you will use it only in a qualified laboratory setting.
| CAS No. | 80714-61-0 |
|---|---|
| Formula | C37H51N9O10S |
| Molecular weight | 813.9 g/mol |
| Purity | ≥ 99% (HPLC) |
| Appearance | White lyophilized powder |
| Availability | In stock |
Product notes
Semax is a synthetic analogue of the adrenocorticotropic hormone (ACTH) 4–10 fragment with an added N-terminal Met-Glu extension and a molecular weight of 813.9. It is widely used in neurobiology work, both in vitro and in animal models.
Supplied as lyophilized powder with a third-party batch report.
Common research applications
- Neurotrophic factor expression studies
- Cognitive and behavioral animal models
- Controlled studies of central peptide mechanisms
These are common research directions only and do not constitute medical advice or claims of efficacy.
Research background
The ACTH(4-10) fragment is associated with neurotrophic effects, and the N-terminal extension in Semax improves stability and duration of action. Common research areas include BDNF expression, neural plasticity and behavioral observations in stress models.
Because this work involves central effects, experimental design must follow your institution's animal ethics and use regulations strictly.
Test methods
- HPLC: C18 reversed-phase column, 220 nm detection, purity integration area ≥ 99%
- LC-MS: ESI positive mode, measured mass within < 0.1% of theoretical
- Endotoxin: sampled per batch, results published with the COA
Specifications
| Product name | Semax |
|---|---|
| Size | 5mg / vial, 10mg / vial |
| CAS | 80714-61-0 |
| Molecular weight | 813.9 g/mol |
| Purity | ≥ 99% (HPLC; measured value per batch shown on COA) |
| Form | Lyophilized powder (white to off-white) |
| Packaging | Light-proof glass vial + rubber stopper + aluminum cap |
| Storage | Unopened: -20°C, protected from light and moisture |
| Test report | Look up by batch number → |
Latest batch report: VP-2406-D
Storage & reconstitution
Unopened: Store at -20°C, protected from light and moisture, and avoid sharp temperature swings. It is stable short-term at ambient temperature in transit; move it to cold storage promptly on receipt.
Reconstitution: Use sterile water for injection or a buffer suited to your assay. Add the solvent slowly down the vial wall and swirl gently to dissolve; avoid vigorous vortexing, which creates bubbles and can denature the peptide.
Aliquoting: After reconstitution, aliquot single-use volumes before freezing and avoid repeated freeze-thaw. Solutions containing preservatives are not suitable for cell culture; choose the solvent according to your system.
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The above is general guidance; confirm concentration, buffer system and storage duration against your own protocol.
How does the vial batch number match the COA?
The vial label carries a unique batch number (e.g. VP-2411-A). Enter it on the COA lookup page to retrieve the HPLC chromatogram and LC-MS result for that batch; the number must match exactly.
What is the difference between the two sizes?
Only the fill volume differs; purity standards and testing are identical. For a first experiment we suggest the smaller size for method validation, then ordering the larger size as needed.
Can you provide a signed original report?
Yes. Note "signed report required" in the order comments and we will include a paper copy; the electronic version can also be downloaded from the COA page.
