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CJC-1295 (No DAC) lyophilized powder vial
CJC-1295 (No DAC) vial detail CJC-1295 (No DAC) lyophilized powder
Research Peptide

CJC-1295 (No DAC)

Mod GRF 1-29 · tetra-substituted fragment

★★★★★ (52 researcher reviews)
$44

Includes 5mg vials. Free shipping over $150.

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HPLC ≥ 99% LC-MS Verified Sterile Vial Batch COA
⚠️
This product is a research compound and must not be used in humans or animals. Placing an order confirms you will use it only in a qualified laboratory setting.
CAS No.863288-34-0
FormulaC152H252N44O42
Molecular weight3367.9 g/mol
Purity≥ 99% (HPLC)
AppearanceWhite lyophilized powder
AvailabilityIn stock

Product notes

CJC-1295 (No DAC), also known as Mod GRF 1-29, is a fragment of natural GHRH(1-29) carrying four amino-acid substitutions that markedly improve its stability in vitro.

This is the version without the DAC maleimide group. Its shorter half-life suits experimental designs that require short observation windows.

Common research applications

  • GHRH receptor agonist mechanism studies
  • Secretion rhythm observations in combination with Ipamorelin
  • Peptide stability and degradation pathway analysis

These are common research directions only and do not constitute medical advice or claims of efficacy.

Research background

Native GHRH is rapidly degraded by dipeptidyl peptidase in vivo. Four site substitutions in Mod GRF 1-29 improve resistance to enzymatic cleavage, making it a common tool peptide for studying growth hormone secretion.

Compared with the long-acting DAC version, the No DAC form has a noticeably shorter half-life in solution, so dosing intervals and sampling points need to be planned accordingly.

Test methods

  • HPLC: C18 reversed-phase column, 220 nm detection, purity integration area ≥ 99%
  • LC-MS: ESI positive mode, measured mass within < 0.1% of theoretical
  • Endotoxin: sampled per batch, results published with the COA

Specifications

Product nameCJC-1295 (No DAC)
Size5mg / vial, 10mg / vial
CAS863288-34-0
Molecular weight3367.9 g/mol
Purity≥ 99% (HPLC; measured value per batch shown on COA)
FormLyophilized powder (white to off-white)
PackagingLight-proof glass vial + rubber stopper + aluminum cap
StorageUnopened: -20°C, protected from light and moisture
Test reportLook up by batch number →

Storage & reconstitution

Unopened: Store at -20°C, protected from light and moisture, and avoid sharp temperature swings. It is stable short-term at ambient temperature in transit; move it to cold storage promptly on receipt.

Reconstitution: Use sterile water for injection or a buffer suited to your assay. Add the solvent slowly down the vial wall and swirl gently to dissolve; avoid vigorous vortexing, which creates bubbles and can denature the peptide.

Aliquoting: After reconstitution, aliquot single-use volumes before freezing and avoid repeated freeze-thaw. Solutions containing preservatives are not suitable for cell culture; choose the solvent according to your system.

ℹ️
The above is general guidance; confirm concentration, buffer system and storage duration against your own protocol.
How does the vial batch number match the COA?

The vial label carries a unique batch number (e.g. VP-2411-A). Enter it on the COA lookup page to retrieve the HPLC chromatogram and LC-MS result for that batch; the number must match exactly.

What is the difference between the two sizes?

Only the fill volume differs; purity standards and testing are identical. For a first experiment we suggest the smaller size for method validation, then ordering the larger size as needed.

Can you provide a signed original report?

Yes. Note "signed report required" in the order comments and we will include a paper copy; the electronic version can also be downloaded from the COA page.

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CJC-1295 (No DAC) · 5mg × 1 $44

For research use only. This is a purchase request; we will confirm availability, payment and delivery before dispatch.

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